Publisher: College of Chemistry and Materials Science 

Date: July 4, 2024

In a groundbreaking exploration at the frontier of regenerative medicine, Professor Luo Binghong's expert team at the School of Chemistry and Materials Science, Jinan University, has engineered a novel liquid crystal ink formulation exemplifying rapid photopolymerization kinetics, ideal viscosity, distinctive liquid crystal properties, and robust three-dimensional retention post-printing. Leveraging Digital Light Processing (DLP) technology, the team successfully crafted a series of three-dimensional liquid crystal scaffolds emulating a bone-like microenvironment, unveiling the profound influence of these innovative scaffolds on stem cell osteogenic differentiation and bone formation. Notably, in vivo assessments have underscored the remarkable efficacy of these liquid crystal scaffolds in facilitating skull defect regeneration, signifying a paradigmatic leap in biomimetic scaffold design for tissue engineering applications.

(Screenshot of the paper)

This seminal research endeavor, elucidated in the esteemed journal Bioactive Materials under the title Illuminating the Osteogenic Realm: Unveiling the Role of Osteoid-like Microenvironment via Light-Curing Liquid Crystal Ink, underscores the transformative potential of bionic scaffolds in orchestrating osteogenesis within intricate biological contexts.

The pioneering efforts are spearheaded by the astute Liu Kun, a prodigious graduate student hailing from the School of Chemistry and Materials Science at Jinan University, with esteemed Professor Luo Binghong assuming the mantle of corresponding authorship. Jinan University emerges as the exclusive affiliated institution heralding this profound research feat.

For a comprehensive dive into this transformative research discourse, interested readers are encouraged to explore the original publication accessible via the following link: [https://doi.org/10.1016/j.bioactmat.2024.06.019].