Time: Oct. 25, 2021 

Source: Guangdong-Hong Kong-Macau Institute of CNS Regeneration

Zhang Li's research group at the Guangdong-Hong Kong-Macao Institute of CNS Regeneration of Jinan University published a research paper titled Physical exercise rescues cocaine-evoked synaptic deficits in motor online in Molecular Psychiatry (Impact Factor: 15.992) on Oct. 22. The paper illustrates the neural mechanism of exercise in post-detox neurological recovery. This is another important achievement by the team in the field of exercise and brain health, following its 2019 paper published in Science Advances, revealing the key molecular pathway of exercise-enhanced cortical synaptogenesis (DOI: 10.1126/sciadv.aaw1888).

The research received support from Su Guohui, a JNU academician, collaborating with Yuan Tifei's team from the Shanghai Mental Health Center. The work was carried out mainly by Cheng Tong, a former JNU graduate student in neurobiology who is now a Ph.D. student at Hong Kong Polytechnic University, with Dr. Huang Xiaodan, Dr. Chen Kai, and students Hu Xuefei, Wang Siqi, Wei Ji'an and Yan Lan also taking part in the research.

The program was also supported by many foundations, including the National Natural Science Foundation of China (Grant No. 32070955, 31771215), the Key Research and Development Project of the Ministry of Science and Technology (Grant No. 2020YFA0113600) and the Guangzhou Major Project on Brain Science (Grant No. 202007030012).

Link to paper: https://www.nature.com/articles/s41380-021-01336-2