Date：June 16, 2021 

Source: Institute of Photonics Technology

The overseas talent innovation team of Jinan University's Institute of Photonics Technology has made significant progress in research on stimulated-emission depletion（STED） microscopy. Now the journal Nature Nanotechnology (IF=31.538) has published the paper Continuous-wave near-infrared stimulated-emission depletion microscopy using downshifting lanthanide nanoparticles. Dr. Liang Liangliang of the National University of Singapore, doctoral student Feng Ziwei of JNU's Institute of Photonics Technology, and Prof. Zhang Qiming of the University of Shanghai for Science and Technology are the first authors. Prof. Liu Xiaogang of the National University of Singapore, Prof. Li Xiangping of JNU's Institute of Photonics Technology and National Academician Gu Min of the University of Shanghai for Science and Technology are the corresponding authors. Collaborators from Nanyang Technological University also contributed to this research.

The international cooperation of Li Xiangping, Liu Xiaogang and Gu Min resulted in the invention of a near-infrared STED microscopy using downshifting lanthanide nanoparticles. This technique realized the sub-20nm single particle super resolution microscopy and 50 μm deep tissue high resolution microscopy.

This research was supported by National Key Research and Development Program of China (2018YFB1107200) and the Guangdong Innovation and Entrepreneurship Team Project (2016ZT06D081).

Link to paper: https://www.nature.com/articles/s41565-021-00927-y.pdf