Time: Nov 26th, 2018
Source: College of Chemistry and Materials Science

An international journal of nano science has published a paper by the targeted nano-drug research team headed by Prof. Chen Tianfeng of JNU's College of Chemistry and Materials Science. The paper, titled 'Bio-Inspired Tumor-Homing Nanosystem for Precise Cancer Therapy by Reprogramming Tumor-Associated Macrophages, was highlighted as the featured article on Oct. 12 in NPG Asia Materials (IF2015-2017,8.379), a subjournal of Nature. Doctoral candidate Huang Yanyu is the first author, and Chen and Prof. Liu Zhuang of Soochow University are project leaders.

The paper concerns a biomimetic nano-drug delivery system with tumor cell membrane that achieved high-efficiency anticancer effects without causing toxic side effects in major organs.

The team's research was supported and funded by the National Special Support Program for High-Level Personnel Recruitment (Youth Talent Support Project), the National Programs for High Technology Research and Development (863 Project), the National Natural Science Foundation, the Guangdong Natural Science Fund for Distinguished Young Scholars and the China Postdoctoral Science Foundation.

Chen's team has long worked on chemical design of targeted nano-drugs and their application and mechanism research in tumor diagnosis. Team members have published more than 200 research papers in the Angewandte Chemie International Edition, ACS Nano, Advanced Functional Materials, Biomaterials and other international journals, 28 of which were selected as journal covers in Advanced Functional Materials, Journal of Materials Chemistry B and other international journals.

Link to paper: https://www.nature.com/articles/s41427-018-0091-9